News
September 2014: The Neurophenols team will presenting at the BENEFIQ, an international forum on health ingredients, which will be held on September 24-25th 2014 in Québec City.
Juin 2014: Alexandre Dal-Pan, Post-doc researcher at INAF, has participated at ISANH Congress at Lisbonne, the june 5th 2014.
December 2013: Nutrineuro laboratory has participated at the last meeting of the Institute of Nutrition Aquitaine Québec (INAQ), the december 10th 2013, in Bordeaux.
October 2013: Julien Bensalem, ACTIV’INSIDE PhD student linked to NUTRINEURO laboratory, won a Young Investigator Award at the " 6th International Congress on Polyphenols and Health" (ICPH6), in Buenos Aires (Argentina), the october 19th 2013.
May 2013: The Neurophenols Project was awarded for the Prix Agrimip des Lycéens 2013. This award is given to honor collaborative projects between scientific, technological, industrial and organizational large groups and academic research, in France (Aquitaine, Bretagne, Pays de la Loire) and Canada (Québec).
Research
The Neurophenols project brings together more than 30 professionals including 22 scientists and engineers focused on research. These scientists are grouped into different cells, each working on a specific part of the project.
On this page, the scientists will keep you posted on research progress.
- Analytical characterization of ingredients
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Yves DESJARDINS Teacher-Researcher at INAF (Laval University, Québec City, CA) |
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Stéphanie DUDONNÉ Post-Doc researcher at INAF (Laval University, Québec City, CA)) |
"It is very important to accurately identify and quantify the active ingredients in a plant extract. This requires finding the best assay for these ingredients.
We tested many techniques of dosage in particular, UPLC. UPLC (Ultra Performance Liquid Chromatography) is used to separate the molecules of a liquid phase and identify them based on their migration on a stationary phase.
Finally, we have developed an assay procedure to determine precisely the amount of pure active ingredient that contains a fruit."
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Marie MICOULEAU Manager at POLYPHENOLS BIOTECH |
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Jean-Michel MERILLON Teacher-Researcher at ISVV (University of Bordeaux, Institute of Sciences of Vine and Wine, FR) |
"We interested in the analytical characterization of the active ingredients of some red fruits and more particularly in a family of polyphenols which may be useful against the dysfunction of brain cells: stilbenes. Our job is to better quantify these active ingredients in complex food matrices in order to understand the impact of transformation processes. We also discuss the mechanisms of action being involved in neuroprotection using cellular model such as microglial cells* lines from mouse brain."
* Microglial are small mobiles cells of the central nervous system. They are macrophages implicating in the immune defense of the brain and the spinal cord.